:root{color-scheme:light;--ink:#172f38;--muted:#536975;--teal:#087f78;--blue:#2e5faa;--red:#ac343d;--platelet:#7c55ad;--fibrin:#c88619;--line:#cbd7dd;font-family:Arial,Helvetica,sans-serif;color:var(--ink)}
.drug-stage-nav .p2-dose-controls{margin-left:auto;display:flex;align-items:center;gap:8px}.drug-stage-nav .p2-dose-controls span{margin:0 5px 0 0}.step-list .p2-dose-controls button{flex:none;border:1px solid var(--line);padding:8px 14px;font-size:18px;text-align:center}.step-list .p2-dose-controls button[aria-pressed=true]{background:var(--blue);border-color:var(--blue);color:#fff}.p2-data-table{border-collapse:collapse;width:100%;font-size:17px}.p2-data-table th,.p2-data-table td{text-align:left;border-bottom:1px solid var(--line);padding:8px}
.p2y12-svg .p2-copy{font-size:23px}.p2y12-svg .p2-number{font-size:43px;font-weight:700}.p2-arrow{fill:none;stroke:#7c55ad;stroke-width:3}.p2-arrow.p2-muted{stroke:#8a97a1;stroke-dasharray:6 7;opacity:.6}.p2-block{fill:none;stroke:#ac343d;stroke-width:4;stroke-linecap:round}.p2-comparison{height:100%;padding:14px 0 0;overflow:auto}.p2-comparison table{border-collapse:collapse;width:100%;font-size:23px;line-height:1.25}.p2-comparison th,.p2-comparison td{padding:19px 16px;text-align:left;border-bottom:1px solid var(--line)}.p2-comparison thead{background:#edf3f8;color:#2e5faa}.p2-comparison tbody th{color:#7443a1}.p2-comparison tbody tr:nth-child(even){background:#f7f4fa}.p2-comparison p{margin:14px 16px 0;font-size:17px;color:var(--muted)}.p2-sr-only{position:absolute;width:1px;height:1px;padding:0;overflow:hidden;clip:rect(0,0,0,0);white-space:nowrap;border:0}@media(max-width:600px){.p2-comparison table{min-width:980px;font-size:19px}.p2-comparison th,.p2-comparison td{padding:14px 12px}.p2-comparison p{font-size:14px}}
.p2-timing{padding-top:6px}.p2-timing table{table-layout:fixed}.p2-timing th,.p2-timing td{padding:11px 16px;vertical-align:middle}.p2-timing th:nth-child(1){width:16%}.p2-timing th:nth-child(2){width:22%}.p2-timing th:nth-child(3){width:18%}.p2-timing th:nth-child(4){width:17%}.p2-timing th:nth-child(5){width:27%}.p2-timing-detail{display:block;font-size:18px;font-weight:400;line-height:1.2;margin-top:3px;color:var(--muted)}.p2-onset strong{color:var(--teal)}.p2-offset strong{color:#7443a1}.p2-timing p{margin-top:10px;font-size:18px}@media(max-width:600px){.p2-timing table{min-width:1100px}.p2-timing-detail{font-size:15px}.p2-timing p{font-size:14px}.drug-expanded .vessel-figure:has(.p2-timing){height:auto;min-height:300px;overflow:auto}}
*{box-sizing:border-box}body{margin:0;background:#10262e;overflow:hidden}button{font:inherit;color:inherit;background:#fff;border:1px solid var(--line);padding:11px 18px;cursor:pointer;font-size:21px;line-height:1.2}button:hover{background:#edf4f6}button:focus-visible,summary:focus-visible,a:focus-visible{outline:4px solid #c58a14;outline-offset:3px}button.primary{background:var(--blue);border-color:var(--blue);color:#fff}button[aria-pressed=true]{background:#e9f3f1;color:#096d67;border-color:var(--teal)}button:disabled{opacity:.42;cursor:default}[hidden]{display:none!important}
#canvas{position:absolute;transform-origin:top left;width:1600px;height:900px;background:#fff;border-top:5px solid var(--teal);display:grid;grid-template-rows:107px 54px 1fr 78px}.lecture-header{display:flex;justify-content:space-between;align-items:center;padding:16px 42px 18px;gap:25px;background:#f7fafb;border-bottom:1px solid var(--line)}.eyebrow{font-weight:700;font-size:16px;letter-spacing:1.8px;text-transform:uppercase;color:var(--teal);margin:0 0 8px}h1{font-size:39px;letter-spacing:-1px;margin:0;line-height:1.1}.header-actions{display:flex;gap:10px}.header-actions button{font-size:18px;padding:10px 14px}.sections{display:flex;align-items:stretch;padding:0 42px;border-bottom:1px solid var(--line);gap:28px}.sections button{font-size:20px;font-weight:700;border:0;background:none;padding:12px 0;border-bottom:4px solid transparent}.sections button[aria-pressed=true]{border-bottom-color:var(--teal);color:var(--teal)}#sectionLocation{margin-left:auto;align-self:center;font-size:17px;color:var(--muted)}
#comparison{padding:26px 42px 0}#comparison h2{font-size:30px;font-weight:400;margin:0 0 26px}.comparison-pair{display:grid;grid-template-columns:1fr 1fr;gap:58px}.comparison-pair article+article{border-left:1px solid var(--line);padding-left:42px}.contrast-name{font-size:35px;font-weight:700;margin:0 0 8px}.protective{color:var(--teal)}.pathologic{color:var(--red)}.definition{font-size:25px;line-height:1.3;margin:0;min-height:67px}.still{height:192px;margin:6px -15px 0}.still svg{width:100%;height:100%}.comparison-pair h3{font-size:25px;margin:10px 0 8px}.comparison-pair article>p:not(.contrast-name):not(.definition){font-size:23px;line-height:1.3;margin:0 0 18px;max-width:640px}.shared-principle{border-top:1px solid var(--line);padding-top:19px;margin:24px 0 0;font-size:24px;color:var(--muted)}
#walkthrough{padding:18px 42px 0;display:grid;grid-template-rows:70px 405px 28px 73px 52px;min-height:0}.stage-heading{display:flex;justify-content:space-between;align-items:start;gap:14px}.stage-heading h2{font-size:31px;line-height:1.12;letter-spacing:-.5px;margin:0}.stage-heading .eyebrow{font-size:14px;margin-bottom:7px}#scenarioControls{display:flex;gap:7px;margin-top:3px}#scenarioControls button{font-size:17px;padding:9px 11px}.vessel-figure{min-height:0;position:relative}.vessel-figure>svg{width:100%;height:100%;overflow:visible}.legend{display:flex;align-items:center;gap:23px;font-size:17px;color:var(--muted)}.legend span{display:flex;align-items:center;gap:7px}.legend .schematic{margin-left:auto;font-size:15px}.key{display:inline-block;width:16px;height:11px}.platelet-key{background:var(--platelet);border-radius:50%}.red-cell-key{background:#c55865;border-radius:50%;width:20px}.fibrin-key{height:3px;background:var(--fibrin);width:25px}.endothelium-key{background:#78b8b2;width:24px;border-radius:5px}.teaching-point{border-top:1px solid var(--line);margin-top:8px;display:flex;gap:24px;align-items:center;padding:10px 0 6px}.teaching-point span{font-size:15px;letter-spacing:1px;font-weight:700;color:var(--teal);text-transform:uppercase;flex:0 0 150px}.teaching-point p{margin:0;font-size:25px;line-height:1.28}.step-list{display:flex;gap:10px;align-items:center}.step-list button{flex:1;font-size:17px;padding:9px 6px;border:0;border-bottom:3px solid var(--line);text-align:left;background:none;white-space:nowrap}.step-list button span{font-weight:700;margin-right:7px}.step-list button[aria-pressed=true]{border-color:var(--teal);color:var(--teal);background:#edf6f4}.playback{border-top:1px solid var(--line);display:flex;justify-content:space-between;gap:18px;align-items:center;padding:14px 42px;background:#f5f8fa}.playback>div{display:flex;gap:9px}.playback button{font-size:20px}.playback>span{font-size:18px;color:var(--muted)}
dialog{width:min(850px,94vw);max-height:88vh;border:1px solid var(--line);border-top:5px solid var(--blue);padding:30px 35px;color:var(--ink);font-size:19px;line-height:1.55;overflow:auto}dialog::backdrop{background:#10262ebb}dialog h2{font-size:29px;line-height:1.15;padding-right:70px}dialog h3{font-size:20px;margin-bottom:3px}dialog p{margin:12px 0}dialog ul{padding-left:25px}#closeNotes{float:right;font-size:17px}dialog details{border-top:1px solid var(--line);margin-top:25px;padding-top:15px;font-size:16px}summary{cursor:pointer;font-weight:700}dialog a{color:var(--blue)}
.vessel-svg text{font-family:Arial,Helvetica,sans-serif;fill:var(--ink);font-size:23px}.vessel-svg .small-label{font-size:18px;fill:var(--muted)}.vessel-svg .label-heading{font-size:24px;font-weight:700}.vessel-svg .label-teal{fill:#087f78}.vessel-svg .label-red{fill:#a52b37}.vessel-svg .label-purple{fill:#71449f}.vessel-svg .label-gold{fill:#93630f}.vessel-svg .leader{fill:none;stroke:#748a92;stroke-width:1.6}.vessel-svg .new-feature{animation:appear .7s ease-out both}.vessel-svg .flow-track{fill:none;stroke:#72a6b7;stroke-width:3;stroke-dasharray:12 16;animation:stream 2s linear infinite}.vessel-svg .fibrin-strand{fill:none;stroke:#c88619;stroke-width:3.2;stroke-linecap:round;stroke-dasharray:360;stroke-dashoffset:0;animation:weave 1.3s ease-out both}.vessel-svg .signal{fill:none;stroke:#9c71ba;stroke-width:2;animation:signal 2.2s ease-out infinite}.vessel-svg .bleed{animation:bleed 1.7s ease-in-out infinite}.vessel-svg .clot-enter{animation:assemble 1.3s ease-out both;transform-box:fill-box;transform-origin:center}.vessel-svg .fragment{animation:embolize 4s linear infinite}.vessel-svg .dissolve{animation:dissolve 3s ease-in-out both}.vessel-svg .cell-stream{animation:travel var(--duration,10s) linear infinite;animation-delay:var(--delay,0s)}
/* Keep labels readable when a moving cell passes beneath them. */
.vessel-svg text{paint-order:stroke fill;stroke:#fff;stroke-width:4px;stroke-linejoin:round}
body.motion-paused .vessel-svg *{animation-play-state:paused!important}
body.static-stage .vessel-svg .new-feature,body.static-stage .vessel-svg .clot-enter,body.static-stage .vessel-svg .fibrin-strand,body.static-stage .vessel-svg .dissolve{animation:none!important}
body.static-stage .vessel-svg .dissolve{opacity:0}
@keyframes stream{to{stroke-dashoffset:-56}}@keyframes travel{from{transform:translateX(-1550px)}to{transform:translateX(1550px)}}@keyframes appear{from{opacity:.15}to{opacity:1}}@keyframes weave{from{stroke-dashoffset:360}to{stroke-dashoffset:0}}@keyframes signal{from{r:25;opacity:.7}to{r:105;opacity:0}}@keyframes bleed{from{transform:translateY(-8px);opacity:.15}60%{opacity:.8}to{transform:translateY(45px);opacity:0}}@keyframes assemble{from{transform:translate(-130px,-55px);opacity:.1}to{transform:translate(0,0);opacity:1}}@keyframes embolize{0%{transform:translate(0,0);opacity:0}12%{opacity:1}85%{opacity:1}100%{transform:translate(440px,-15px);opacity:0}}@keyframes dissolve{0%{opacity:.6}100%{opacity:0}}
@media(prefers-reduced-motion:reduce){.vessel-svg *{animation:none!important}.vessel-svg .dissolve{opacity:0}}
@media(max-width:600px){body{overflow:auto;background:#fff}#canvas{position:relative!important;transform:none!important;left:0!important;top:0!important;width:100%;height:auto;display:block}.lecture-header{padding:17px;display:block}h1{font-size:27px}.eyebrow{font-size:11px}.header-actions{margin-top:13px}.header-actions button{font-size:15px}.sections{padding:0 17px;gap:15px}.sections button{font-size:14px}#sectionLocation{display:none}#comparison{padding:20px 17px}#comparison h2{font-size:22px}.comparison-pair{display:block}.comparison-pair article+article{border-left:0;border-top:1px solid var(--line);padding:23px 0 0;margin-top:25px}.contrast-name{font-size:29px}.definition{font-size:20px;min-height:0}.comparison-pair article>p:not(.contrast-name):not(.definition){font-size:19px}.comparison-pair h3{font-size:22px}.shared-principle{font-size:18px}.still{height:170px}#walkthrough{display:block;padding:18px 17px}.stage-heading{display:block}.stage-heading h2{font-size:25px}#scenarioControls{margin-top:15px;flex-wrap:wrap}#scenarioControls button{font-size:14px}.vessel-figure{height:260px;overflow:auto;margin:10px -17px}.vessel-figure>svg{width:840px;max-width:none}.legend{flex-wrap:wrap;font-size:13px;gap:9px}.legend .schematic{flex-basis:100%;font-size:12px}.teaching-point{display:block;padding:16px 0}.teaching-point span{font-size:12px}.teaching-point p{font-size:20px;margin-top:6px}.step-list{flex-wrap:wrap;gap:7px}.step-list button{flex:1 0 27%;font-size:14px;white-space:normal;min-height:44px}.playback{padding:15px 17px;flex-wrap:wrap;gap:12px}.playback>div{flex-wrap:wrap}.playback button{font-size:15px;min-height:44px}.playback>span{order:3;flex-basis:100%;font-size:14px}dialog{padding:20px;font-size:17px}}
/* Opening cover shares the lecture canvas and leaves the existing chapter numbering intact. */
#canvas.title-page{grid-template-rows:107px 1fr 78px}
.title-page .lecture-header{justify-content:flex-end;background:#fff;border-bottom:0}
.title-slide{position:relative;display:flex;align-items:center;padding:0 112px 74px;min-height:0}
.title-slide-copy{position:relative;z-index:1;max-width:1000px}
.title-slide h1{font-size:88px;line-height:1.05;letter-spacing:-2.7px;color:var(--ink);margin:0 0 28px}
.title-slide-subtitle{font-size:32px;line-height:1.3;color:var(--teal);margin:0}
.title-slide-credit{font-size:26px;line-height:1.3;color:var(--muted);margin:56px 0 0}
.title-slide-icon{position:absolute;width:540px;height:540px;object-fit:contain;right:90px;top:10px}
.title-slide-logo{position:absolute;width:82px;height:auto;object-fit:contain;right:42px;bottom:28px}
.title-page .playback{justify-content:flex-end}
.title-page .playback>span{margin-right:auto}
@media(max-width:600px){
  .title-page .lecture-header{display:flex;padding:17px}
  .title-page .header-actions{margin-top:0}
  .title-slide{display:block;padding:12px 24px 146px;min-height:640px}
  .title-slide-icon{position:static;display:block;width:min(100%,320px);height:auto;margin:30px auto 0}
  .title-slide-copy{display:flex;flex-direction:column}
  .title-slide h1{font-size:clamp(32px,8.8vw,48px);letter-spacing:-1.1px;margin-bottom:20px}
  .title-slide-subtitle{font-size:23px}
  .title-slide-credit{font-size:19px;margin-top:32px}
  .title-slide-logo{width:64px;right:24px;bottom:25px}
  .title-page .playback>span{order:0;flex-basis:auto}
}
/* One shared seven-step vocabulary, with relationships clarified in plain language. */
.framework-slide{padding:20px 42px 16px;min-height:0}
.framework-intro h2{font-size:32px;line-height:1.15;letter-spacing:-.5px;margin:0 0 10px}
.framework-intro>p:last-child{font-size:23px;margin:0;color:var(--ink)}
.framework-context{font-size:21px;line-height:1.3;color:var(--muted);margin:10px 0 0}
.framework-map{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:36px 30px;list-style:none;margin:32px 0;padding:0}
.framework-map>li{min-width:0;border-top:2px solid var(--line);padding-top:14px}
.framework-number{font-weight:700;color:var(--teal);margin-right:5px}
.framework-map h3{font-size:25px;line-height:1.18;margin:0 0 12px}
.framework-map p{font-size:22px;line-height:1.3;color:var(--muted);margin:0}
.framework-relationships{font-size:22px;line-height:1.45;max-width:1270px;margin:24px 0 30px}
.framework-bottom{display:flex;align-items:center;justify-content:space-between;gap:24px;border-top:1px solid var(--line);margin-top:16px;padding-top:12px}
.framework-bottom p{font-size:23px;line-height:1.3;margin:0;max-width:1000px}
.framework-bottom a{font-size:19px;color:var(--blue);text-underline-offset:3px}
.framework-note{border-left:3px solid var(--teal);padding-left:16px;margin:20px 0}
.framework-check{border-top:1px solid var(--line);margin-top:22px;padding-top:8px}
.framework-check ol{padding-left:28px}.framework-check li{padding:4px 0}
.framework-check details{margin-top:12px}
@media(max-width:600px){
  .framework-slide{padding:22px 17px}
  .framework-intro h2{font-size:26px}
  .framework-intro>p:last-child{font-size:19px}
  .framework-context{font-size:18px}
  .framework-map{grid-template-columns:1fr;gap:18px;margin:24px 0}
  .framework-map h3{font-size:22px;margin:0 0 5px}
  .framework-map p,.framework-relationships{font-size:19px}
  .framework-bottom{display:block}
  .framework-bottom a{display:block;margin-top:12px}
  .framework-bottom p{font-size:20px}
  .framework-bottom a{font-size:18px}
}
/* Platelet detail uses the same teaching canvas; no miniature diagram or scrolling on desktop. */
#walkthrough.platelet-expanded{grid-template-rows:70px 385px 44px 77px 52px}
.platelet-details{display:flex;align-items:center;gap:8px;border-top:1px solid #e4d8ed;padding-top:5px}
.platelet-details button{flex:1;font-size:17px;padding:8px 8px;border:0;background:#f6f2fa;color:#665078;white-space:nowrap}
.platelet-details button span{font-weight:700}
.platelet-details button[aria-pressed=true]{background:#7c55ad;color:white}
.coagulation-details{gap:5px;border-top-color:#eadfc9}
.coagulation-details button{font-size:16px;padding:9px 5px;background:#fbf6ec;color:#795c28}
.coagulation-details button[aria-pressed=true]{background:#916414;color:white}
.cd-factor rect{fill:#e7f3f0;stroke:#197e78;stroke-width:2}
.cd-factor.cd-cofactor rect,.cd-factor.cd-platelet rect{fill:#f0e7f6;stroke:#8054ac}
.cd-factor.cd-substrate rect{fill:#f4f7f9;stroke:#9bafb9}
.cd-factor.cd-surface rect{fill:#cde3dd;stroke:#197e78}
.coagulation-detail-svg .cd-factor-label{font-size:24px;font-weight:700;stroke:none}
.cd-arrow{fill:none;stroke:#197e78;stroke-width:2.5;stroke-linejoin:round}
.coagulation-detail-svg .cd-dashed{stroke-dasharray:8 6;animation:pd-reveal .65s ease-out var(--delay,0s) both}
.cd-anchor{fill:none;stroke:#197e78;stroke-width:2}
.cd-calcium{fill:#e9f4f1;stroke:#197e78;stroke-width:1.5}
.coagulation-detail-svg .cd-calcium-label{font-size:13px;stroke:none;fill:#116d66}
.coagulation-detail-svg .cd-fibrin{fill:#f6dfa5;stroke:#a77319}
.cd-fibrin .pd-fib-central{fill:#f8e9c6}
.cd-fibrin .pd-fib-coil{stroke:#a77319}
.cd-knob{fill:#197e78;stroke:#197e78;stroke-width:2}
.cd-peptide{fill:#9469b0}
.cd-fiber{fill:none;stroke:#c88619;stroke-width:6;stroke-linecap:round}
.cd-crosslink{fill:none;stroke:#2e5faa;stroke-width:4;stroke-linecap:round}
.platelet-detail-svg text{font-size:22px;stroke-width:3px}
.platelet-detail-svg .pd-heading{font-size:27px;font-weight:700}
.platelet-detail-svg .pd-medium{font-size:23px}
.platelet-detail-svg .pd-small{font-size:18px}
.platelet-detail-svg .pd-muted{fill:#536975}
.platelet-detail-svg .pd-purple{fill:#7443a1}
.platelet-detail-svg .pd-teal{fill:#087f78}
.platelet-detail-svg .pd-gold{fill:#93630f}
.platelet-detail-svg .pd-slate{fill:#4b6e81}
.pd-arrow{fill:none;stroke:#7c55ad;stroke-width:2.5;stroke-linejoin:round}
.pd-leader{fill:none;stroke:#748a92;stroke-width:1.5}
.pd-node{fill:#f7f1fc;stroke:#bba1d0;stroke-width:1.5}
.platelet-detail-svg .pd-receptor{font-size:23px;font-weight:700;fill:#7443a1;stroke:#eee5f5}
.pd-cell{fill:#e7d9f1;stroke:#8054ac;stroke-width:3;stroke-linejoin:round}
.pd-granule{fill:#8054ac;stroke:none}
.pd-fibrinogen{fill:#c3d5de;stroke:#5a7e91;stroke-width:2.5}
.pd-fibrinogen path{fill:none;stroke-linecap:round}
.pd-fibrinogen .pd-fib-coil{stroke-width:2}
.pd-fibrinogen .pd-fib-tail{stroke:#ad4825;stroke-width:3}
.pd-fib-central{fill:#e2ebef}
.platelet-detail-svg .pd-fib-letter{font-size:16px;font-weight:700;fill:#35566a;stroke:none}
.pd-binding-site{fill:#c6512a;stroke:#fff;stroke-width:1.5}
.platelet-detail-svg .pd-binding-label{fill:#a44020}
.pd-trace{stroke-dasharray:1200;animation:pd-trace 1.25s ease-out var(--delay,0s) both}
.pd-reveal{animation:pd-reveal .65s ease-out var(--delay,0s) both}
.pd-shape-change{transform-box:fill-box;transform-origin:center;animation:pd-shape .9s ease-out both}
.pd-integrin-open{transform-box:fill-box;transform-origin:center bottom;animation:pd-open 1s ease-out both}
.pd-approach{animation:pd-approach 1s ease-out both}
body.static-stage .platelet-detail-svg *{animation:none!important}
@keyframes pd-trace{from{stroke-dashoffset:1200}to{stroke-dashoffset:0}}
@keyframes pd-reveal{from{opacity:.1}to{opacity:1}}
@keyframes pd-shape{from{transform:scale(.8,.65)}to{transform:scale(1,1)}}
@keyframes pd-open{from{transform:scaleY(.6)}to{transform:scaleY(1)}}
@keyframes pd-approach{from{transform:translateX(45px)}to{transform:translateX(0)}}
@media(max-width:600px){.platelet-details{flex-wrap:wrap;padding-bottom:8px}.platelet-details button{flex:1 0 30%;font-size:13px;white-space:normal;min-height:44px}.platelet-expanded .vessel-figure{height:290px}.platelet-expanded .vessel-figure>svg{width:1110px}}
@media(prefers-reduced-motion:reduce){.platelet-detail-svg *{animation:none!important}}
/* Preserve one large scale across all four states; only the balance and intervention change. */
#walkthrough.balance-expanded{grid-template-rows:70px 385px 44px 77px 52px}
.balance-tools{display:flex;justify-content:space-between;align-items:center;gap:20px;border-top:1px solid var(--line);font-size:16px;color:var(--muted)}
#balanceTherapies{display:flex;gap:8px;align-items:center}
#balanceTherapies button{font-size:17px;padding:7px 12px}
.balance-svg text{stroke:none}
.balance-svg .balance-column{font-size:21px;font-weight:700;letter-spacing:.5px}
.balance-svg .balance-force-label{font-size:21px;font-weight:700}
.balance-svg .balance-small{font-size:18px;fill:var(--muted)}
.balance-svg .balance-caption{font-size:18px;font-weight:700}
.balance-svg .balance-pro{fill:#99641e}
.balance-svg .balance-anti{fill:#087f78}
.balance-svg .balance-model-label{font-size:17px;font-weight:700;letter-spacing:1px;fill:var(--muted)}
.balance-svg .balance-pan-label{font-size:18px;font-weight:700;fill:var(--muted)}
.balance-svg .balance-outcome{font-size:23px;font-weight:700}
.balance-connection{margin-top:24px;padding-top:22px;border-top:3px solid var(--teal)}
.balance-connection .eyebrow{font-size:13px;letter-spacing:1px;margin:0 0 7px}
.balance-connection h3{font-size:24px;margin:0 0 10px}
.edge-pair{display:grid;grid-template-columns:1fr 1fr;gap:12px;margin-top:16px}
.edge-pair article{padding:14px 16px;border-left:4px solid var(--teal);background:#edf6f3}
.edge-pair .edge-risk{border-color:var(--red);background:#fbefed}
.edge-pair h4{font-size:17px;margin:0;color:var(--teal)}
.edge-pair .edge-risk h4{color:var(--red)}
.edge-pair p{font-size:18px;line-height:1.4;margin:7px 0 0}
.balance-connection .edge-caveat{font-size:15px;color:var(--muted);margin-top:14px}
@media(max-width:600px){.edge-pair{grid-template-columns:1fr}}
.balance-beam,.balance-pan,.balance-weight{transform-box:view-box;transform-origin:0 0}
.balance-beam{transform:rotate(var(--beam-to));animation:balance-tilt 1.15s ease-in-out both}
.balance-pan{transform:rotate(var(--pan-to));animation:balance-level 1.15s ease-in-out both}
.balance-weight{transform:scaleY(var(--weight-to));animation:balance-mass 1.15s ease-in-out both}
@keyframes balance-tilt{from{transform:rotate(var(--beam-from))}to{transform:rotate(var(--beam-to))}}
@keyframes balance-level{from{transform:rotate(var(--pan-from))}to{transform:rotate(var(--pan-to))}}
@keyframes balance-mass{from{transform:scaleY(var(--weight-from))}to{transform:scaleY(var(--weight-to))}}
body.static-stage .balance-svg *{animation:none!important}
@media(max-width:600px){.sections{display:grid;grid-template-columns:1fr 1fr;gap:0 16px}.sections button{font-size:14px;white-space:normal;text-align:left}.balance-expanded .vessel-figure{height:300px}.balance-expanded .vessel-figure>svg{width:1110px}.balance-tools{display:block;padding:10px 0}#balanceModelNote{font-size:13px}#balanceTherapies{flex-wrap:wrap;margin-top:10px;gap:7px}#balanceTherapies>span{flex-basis:100%;font-size:14px}#balanceTherapies button{font-size:14px;padding:10px;min-height:44px}.balance-expanded .step-list button{flex-basis:43%}}
@media(prefers-reduced-motion:reduce){.balance-svg *{animation:none!important}}
@media print{body{overflow:visible;background:#fff}#canvas{position:relative;left:0!important;top:0!important;transform:none!important}button,.sections,.playback{visibility:hidden}.vessel-svg *{animation:none!important}}
/* Drug chapters retain the large teaching figure and use a selector for longer sequences. */
/* Reserve room for the brief eighth section without shrinking the navigation text. */
.sections{gap:18px}.sections button{font-size:19px;white-space:nowrap}#sectionLocation{font-size:15px}
/* Keep ten section links at the existing readable type size; omit the redundant location caption. */
.sections-with-capstone{gap:14px}.sections-with-capstone #sectionLocation{display:none}
#walkthrough.drug-expanded{grid-template-rows:70px 385px 44px 77px 52px}
/* A hidden tools row must not leave a reserved grid track. Give its height to the figure. */
#walkthrough.drug-expanded.drug-tools-empty{grid-template-rows:70px 429px 77px 52px}
.drug-tools{display:flex;align-items:center;justify-content:space-between;gap:16px;border-top:1px solid var(--line);font-size:16px;color:var(--muted)}
.drug-tools>div{display:flex;gap:8px}.drug-tools button{font-size:17px;padding:8px 12px}.drug-tools button[aria-pressed=true]{background:#7c55ad;color:#fff;border-color:#7c55ad}
.drug-stage-nav{display:flex;align-items:center;gap:20px;width:100%;font-size:18px}.drug-stage-nav label{font-weight:bold;color:var(--teal)}.drug-stage-nav select{font:inherit;color:var(--ink);padding:9px 14px;border:1px solid var(--line);background:white;min-width:380px;max-width:100%}.drug-stage-nav span{margin-left:auto;color:var(--muted);font-size:16px}
select:focus-visible{outline:4px solid #c58a14;outline-offset:2px}
.aspirin-svg text{stroke:none;font-size:24px}.aspirin-svg .ap-small{font-size:18px}.aspirin-svg .ap-bold{font-size:25px;font-weight:700}.aspirin-svg .ap-large{font-size:29px;font-weight:700}.aspirin-svg .ap-node-text{font-size:24px;font-weight:700}
.ap-box{fill:#f6f8fa;stroke:#becdd5;stroke-width:1.5}.ap-box.ap-purple-box{fill:#f1eaf7;stroke:#b79dcb}.ap-box.ap-teal-box{fill:#edf6f3;stroke:#a5c9bc}.ap-box.ap-red-box{fill:#fbefed;stroke:#d9b1ad}.ap-box.ap-blue-box{fill:#eaf0f9;stroke:#a9bddc}.ap-box.ap-soft{fill:#f7f9fa}.ap-box.ap-off{fill:#f2f1f1;stroke:#c6c6c6;stroke-dasharray:7 5}
.p2y12-svg .ap-box.p2-variability-callout{stroke:#ac343d;stroke-width:1;vector-effect:non-scaling-stroke}
.p2y12-svg .p2-clearance-caption{font-size:20px}
.aspirin-svg .ap-target-title{font-size:26px;font-weight:700}
.aspirin-svg .ap-target-major .ap-target-title{font-size:28px}
.aspirin-svg .ap-target-copy{font-size:24px}
.aspirin-svg .ap-target-secondary{font-size:22px}
.aspirin-svg .ap-target-detail{font-size:19px;fill:var(--muted)}
.aspirin-svg .ap-target-kicker{font-size:16px;font-weight:700;letter-spacing:1px}
.ap-arrow{fill:none;stroke:#7c55ad;stroke-width:3;stroke-linejoin:round}.ap-arrow.ap-muted{stroke:#9fadb6;stroke-dasharray:8 7}.ap-block{stroke:#ac343d;stroke-width:5;fill:none;stroke-linecap:round}.aspirin-svg .ap-purple{fill:#7443a1}.aspirin-svg .ap-teal{fill:#087f78}.aspirin-svg .ap-blue{fill:#2e5faa}.aspirin-svg .ap-red{fill:#ac343d}.ap-effect{animation:appear .65s ease-out both}
.aspirin-svg .ap-arrow{stroke-dasharray:1500;animation:ap-flow 1s ease-out both}.aspirin-svg .ap-arrow.ap-muted{stroke-dasharray:8 7;animation:none}
.aspirin-svg .ap-ibu-route{stroke:#2e5faa}.aspirin-svg .ap-interaction-copy{font-size:22px}.aspirin-svg .ap-interaction-number{font-size:42px;font-weight:700}
@keyframes ap-flow{from{stroke-dashoffset:1500}to{stroke-dashoffset:0}}
/* Two instructor-controlled, play-once acetylation scenes. Base styles are complete static endpoints. */
.aspirin-acetylation-svg .ac-copy{font-size:22px}.aspirin-acetylation-svg .ac-token-text{font-size:22px;font-weight:700;fill:#fff}
.aspirin-acetylation-svg .ap-arrow{animation:none;stroke-dasharray:none}
.ac-substrate-route{fill:none;stroke:#9fc9c3;stroke-width:2;stroke-dasharray:5 6}
.ac-pathway-muted{opacity:.38}.ac-pathway-on{opacity:1}
.ac-signal-route{fill:none;stroke:#bc797e;stroke-width:2;stroke-dasharray:6 6}
.ac-covalent-bond{fill:none;stroke:#ac343d;stroke-width:6;stroke-linecap:round}.ac-acetyl-leader{fill:none;stroke:#ac343d;stroke-width:2}
.ac-aa-consumed{opacity:0;animation:ac-consume 2.2s ease-in-out both}
.ac-pgh2-particle{opacity:0;animation:ac-product 1.3s ease-in-out 1.7s both}
.ac-txa-first{animation:ac-txa-first 1.8s ease-in-out 2.7s both}.ac-txa-second{animation:ac-txa-second 2s ease-in-out 3.1s both}
.ac-cell-activated{opacity:1;animation:ac-activate .6s ease-out both}.ac-cell-0{animation-delay:4.1s}.ac-cell-1{animation-delay:4.7s}
.ac-transfer{animation:ac-transfer 2.1s ease-in-out both}.ac-donor{opacity:0;animation:ac-donor 3.3s ease-in-out both}
.ac-bond-forms,.ac-acetyl-caption{animation:ac-activate .4s ease-out 1.8s both}
.ac-free-clears{opacity:0;animation:ac-clear 1.9s ease-out 3.3s both}.ac-clear-caption{opacity:1;animation:ac-activate .5s ease-out 5.2s both}
.ac-aa-challenge{opacity:1;animation:ac-challenge 3.6s ease-in-out 5.3s both}
.ac-entry-blocked{animation:ac-activate .3s ease-out 7.7s both}.ac-recoil-route{fill:none;stroke:#087f78;stroke-width:2}
@keyframes ac-consume{0%,12%{opacity:1;transform:translate(-212px,-52px)}60%{opacity:1;transform:translate(0,-52px)}85%{opacity:1;transform:translate(0,0)}100%{opacity:0;transform:translate(0,0)}}
@keyframes ac-product{0%{opacity:0;transform:translate(-162px,0)}15%{opacity:1}80%{opacity:1;transform:translate(0,0)}100%{opacity:0;transform:translate(0,0)}}
@keyframes ac-txa-first{0%{opacity:0;transform:translate(-189px,53px)}12%{opacity:1}100%{opacity:1;transform:translate(0,0)}}
@keyframes ac-txa-second{0%{opacity:0;transform:translate(-304px,-38px)}12%{opacity:1}100%{opacity:1;transform:translate(0,0)}}
@keyframes ac-activate{from{opacity:0}to{opacity:1}}
@keyframes ac-transfer{0%,10%{transform:translate(-170px,-45px)}100%{transform:translate(0,0)}}
@keyframes ac-donor{0%,6%{opacity:1;transform:translate(-170px,-45px)}64%{opacity:1;transform:translate(0,0)}100%{opacity:0;transform:translate(-90px,-95px)}}
@keyframes ac-clear{0%,15%{opacity:1}100%{opacity:0}}
@keyframes ac-challenge{0%{opacity:0;transform:translate(-47px,-10px)}8%{opacity:1;transform:translate(-47px,-10px)}32%{transform:translate(57px,-37px)}50%{transform:translate(110px,-52px)}60%,70%{transform:translate(165px,-48px)}83%{transform:translate(110px,-52px)}92%{transform:translate(57px,-37px)}100%{opacity:1;transform:translate(0,0)}}
/* One guided exposure/renewal story, with a stable platelet pool across later views. */
.drug-tools.journey-tools>div{display:grid;grid-template-columns:repeat(var(--drug-sequence-count,9),minmax(0,1fr));gap:5px;width:100%}.drug-tools.journey-tools button{padding:8px 4px;font-size:16px;white-space:nowrap}
.drug-stage-nav .drug-view-toggle{flex:0 0 auto;margin-left:auto;padding:9px 14px;border:1px solid #b79dcb;background:#f6f2fa;color:#7443a1;font-size:17px;text-align:center;white-space:nowrap}.drug-stage-nav .drug-view-toggle:hover{background:#eee4f7}
@media(max-width:600px){.drug-stage-nav .drug-view-toggle{margin:12px 0 0;min-height:44px;width:100%;white-space:normal}}
.aspirin-journey-svg .aj-small{font-size:18px}.aspirin-journey-svg .aj-bold{font-size:24px;font-weight:700}.aspirin-journey-svg .aj-question{font-size:29px;font-weight:700}.aspirin-journey-svg .aj-number{font-size:42px;font-weight:700}.aspirin-journey-svg .aj-muted{fill:#536975}.aspirin-journey-svg .aj-blue{fill:#2e5faa}.aspirin-journey-svg .aj-purple{fill:#7443a1}.aspirin-journey-svg .aj-red{fill:#ac343d}
.aspirin-journey-svg .aj-chart-label{font-size:23px;font-weight:600}.aspirin-journey-svg .aj-chart-tick{font-size:21px}.aspirin-journey-svg .aj-chart-copy{font-size:22px}.aj-chart-axis{fill:none;stroke:#304953;stroke-width:2}.aj-chart-grid{fill:none;stroke:#dce5e9;stroke-width:1}.aj-chart-threshold-band{fill:#f0e8f7;stroke:none}.aj-chart-guide{fill:none;stroke-width:2;stroke-dasharray:7 5}.aj-chart-guide-partial{stroke:#2e5faa}.aj-chart-guide-complete{stroke:#7443a1}.aj-response-curve{fill:none;stroke:#21854b;stroke-width:6;stroke-linecap:round;stroke-linejoin:round}.aj-chart-point{stroke:#fff;stroke-width:2.5}.aj-chart-point-partial{fill:#2e5faa}.aj-chart-point-complete{fill:#7443a1}.aj-chart-partial-card{fill:#f3f7fc;stroke:#b3c7e0}
.aj-box{fill:#f7f9fa;stroke:#cbd7dd;stroke-width:1.5}.aj-treated{fill:#f5f0f9;stroke:#bca3d0}.aj-pool{fill:#f5fafb;stroke:#74aaa5;stroke-width:2}.aj-readout{fill:#faf7fc;stroke:#cbb7da}.aj-vessel{fill:#f5fafb;stroke:#74aaa5;stroke-width:3}.aj-gut{fill:none;stroke:#be906e;stroke-width:10;stroke-linecap:round}.aj-flow{fill:none;stroke:#7c55ad;stroke-width:3}.aj-axis{fill:none;stroke:#a0afb6;stroke-width:2}.aj-clearance-curve{fill:none;stroke:#2e5faa;stroke-width:4;stroke-dasharray:420;animation:aj-clearance 2.2s ease-out both}.aj-acetyl{fill:none;stroke:#ac343d;stroke-width:5;stroke-linecap:round}.aj-functional{fill:#087f78;stroke:#fff;stroke-width:2}
.aj-target-before{opacity:0;animation:aj-before 1.5s ease-in-out both;animation-delay:var(--aj-delay,0s)}.aj-target-after{opacity:1;animation:aj-after 1.5s ease-in-out both;animation-delay:var(--aj-delay,0s)}.aj-portal-drug{opacity:0;animation:aj-portal 1.7s ease-in-out both;animation-delay:var(--aj-delay,0s)}.aj-redose-drug{opacity:0;animation:aj-redose 1.4s ease-in-out both;animation-delay:var(--aj-delay,0s)}.aj-clear-drug{opacity:0;animation:aj-clear-drug 2.4s ease-out both;animation-delay:var(--aj-delay,0s)}.aj-new-cell{animation:aj-renewal 1.65s ease-out both;animation-delay:var(--aj-delay,0s)}
@keyframes aj-before{0%,40%{opacity:1}75%,100%{opacity:0}}@keyframes aj-after{0%,40%{opacity:0}75%,100%{opacity:1}}@keyframes aj-portal{0%{opacity:0;transform:translate(-25px,0)}20%{opacity:1}75%{opacity:1;transform:translate(26px,28px)}100%{opacity:0;transform:translate(26px,28px)}}@keyframes aj-redose{0%{opacity:1;transform:translate(0,-28px)}65%{opacity:1;transform:translate(0,20px)}100%{opacity:0;transform:translate(0,26px)}}@keyframes aj-clear-drug{0%,15%{opacity:1}100%{opacity:0}}@keyframes aj-clearance{from{stroke-dashoffset:420}to{stroke-dashoffset:0}}@keyframes aj-renewal{from{opacity:0;transform:translate(-105px,0)}to{opacity:1;transform:translate(0,0)}}
.aspirin-journey-svg[data-choice=portal] .aj-target-before{animation-name:aj-portal-before;animation-duration:1.7s}.aspirin-journey-svg[data-choice=portal] .aj-target-after{animation-name:aj-portal-after;animation-duration:1.7s}
.aspirin-journey-svg[data-choice=suppression] .aj-redose-drug{animation-name:aj-suppression-dose}
@keyframes aj-suppression-dose{0%{opacity:1;transform:translate(0,-5px)}65%{opacity:1;transform:translate(0,20px)}100%{opacity:0;transform:translate(0,26px)}}
@keyframes aj-portal-before{0%,75%{opacity:1}90%,100%{opacity:0}}@keyframes aj-portal-after{0%,75%{opacity:0}90%,100%{opacity:1}}
@media(max-width:600px){.drug-tools.journey-tools>div{grid-template-columns:repeat(3,minmax(0,1fr))}.drug-tools.journey-tools button{font-size:13px;white-space:normal;min-height:44px}}
body.static-stage .aspirin-svg *{animation:none!important}
.aspirin-selectivity-svg .as-small{font-size:18px}.aspirin-selectivity-svg .as-bold{font-size:24px;font-weight:700}.aspirin-selectivity-svg .as-large{font-size:30px;font-weight:700}.aspirin-selectivity-svg .as-muted{fill:#536975}.aspirin-selectivity-svg .as-purple{fill:#7443a1}.aspirin-selectivity-svg .as-red{fill:#ac343d}.aspirin-selectivity-svg .as-blue{fill:#226c92}
.as-box{fill:#f7f9fa;stroke:#cbd7dd;stroke-width:1.5}.as-box.as-platelet-box{fill:#fcf4f2;stroke:#d8b8b5}.as-box.as-endo-box{fill:#eff7fa;stroke:#a8c7d6}.as-arrow{fill:none;stroke:#7c55ad;stroke-width:3;stroke-linejoin:round}.as-arrow.as-blue-arrow{stroke:#226c92}.as-cross{fill:none;stroke:#ac343d;stroke-width:5;stroke-linecap:round}.as-vessel{fill:#f5fafb;stroke:#74aaa5;stroke-width:3}.as-reference-beam{fill:none;stroke:#bbcbd1;stroke-width:3;stroke-dasharray:8 7}.as-balance-beam{fill:none;stroke:#304953;stroke-width:9;stroke-linecap:round}
.as-new-enzyme{opacity:1;animation:as-enzyme-replacement 1.6s ease-out both}.as-exposure-drug{animation:as-drug-exposure 1.7s ease-out both}
.aspirin-uses-svg .au-small{font-size:18px}.aspirin-uses-svg .au-bold{font-size:24px;font-weight:700}.aspirin-uses-svg .au-large{font-size:31px;font-weight:700}.aspirin-uses-svg .au-number{fill:#fff;font-size:24px;font-weight:700}.aspirin-uses-svg .au-muted{fill:#536975}.aspirin-uses-svg .au-purple{fill:#7443a1}.aspirin-uses-svg .au-blue{fill:#226c92}.aspirin-uses-svg .au-teal{fill:#087f78}.aspirin-uses-svg .au-red{fill:#ac343d}
.au-box{fill:#f7f9fa;stroke:#c4d1d9;stroke-width:1.5}.au-box.au-purple-box{fill:#f1eaf7;stroke:#b79dcb}.au-box.au-teal-box{fill:#edf6f3;stroke:#a5c9bc}.au-box.au-red-box{fill:#fbefed;stroke:#d9b1ad}.au-box.au-blue-box{fill:#eff7fa;stroke:#a8c7d6}.au-arrow{fill:none;stroke:#7c55ad;stroke-width:3;stroke-linejoin:round}.au-time-line{fill:none;stroke:#b79dcb;stroke-width:3}.au-divider{stroke:#c4d1d9;stroke-width:1.5}
@keyframes as-enzyme-replacement{from{opacity:0;transform:translateY(12px)}to{opacity:1;transform:translateY(0)}}@keyframes as-drug-exposure{from{opacity:.2;transform:translateX(-12px)}to{opacity:1;transform:translateX(0)}}
.ap-quiz{height:100%;overflow:auto;padding:2px 3px 5px;font-size:21px}.ap-question-tabs{display:flex;gap:8px;align-items:center}.ap-question-tabs button{font-size:17px;padding:8px 12px}.ap-question-tabs [data-retry]{margin-left:auto}.ap-stem{max-width:1360px;line-height:1.35;margin:12px 0 8px}.ap-quiz h3{font-size:26px;margin:7px 0 12px}.ap-answers{display:grid;grid-template-columns:1fr 1fr;gap:9px}.ap-answers button{display:flex;gap:16px;text-align:left;align-items:center;font-size:20px;min-height:52px;padding:10px 13px}.ap-answers button span{color:#7443a1;font-weight:bold}.ap-answers button:disabled{opacity:1}.ap-answers .ap-correct{background:#edf6f3;border-color:#087f78}.ap-answers .ap-wrong{background:#fbefed;border-color:#ac343d}.ap-feedback{font-size:18px;line-height:1.4;margin-top:12px;padding:10px 14px;background:#f4f6f9;border-left:4px solid #7c55ad}.ap-feedback details{margin-top:8px}.ap-feedback details p{margin:8px 0}
.ap-summary{height:100%;overflow:auto;padding:12px 28px 10px;font-size:27px;line-height:1.3}
.ap-summary ul{margin:0;padding-left:30px;display:grid;gap:12px}
.ap-summary li{padding-left:6px}
.ap-summary li::marker{color:var(--teal)}
.ap-summary strong{color:var(--ink)}
.framework-worked{padding:12px 8px;font-size:24px}
.framework-worked dl{display:grid;grid-template-columns:285px 1fr;gap:13px 24px;margin:0}
.framework-worked dt{font-weight:700}.framework-worked dd{margin:0}
.framework-worked .focus-step{color:#075e59;font-weight:700}
@media(max-width:600px){.framework-worked dl{grid-template-columns:1fr;gap:4px}.framework-worked dd{margin-bottom:12px}}
.clinical-balance-summary{font-size:30px;line-height:1.3}.clinical-balance-summary ul{gap:18px}
.drug-stage-nav .optional-deep-dive{margin-left:auto;font-size:17px;line-height:1.35;color:var(--blue);text-decoration:underline;text-underline-offset:3px;max-width:50%}.optional-deep-dive:focus-visible{outline:3px solid var(--teal);outline-offset:4px}
@media(max-width:600px){.drug-stage-nav .optional-deep-dive{display:block;max-width:none;margin:10px 0 0;padding:10px 0;font-size:15px;min-height:44px;box-sizing:border-box}}
.aspirin-bleeding-management{height:100%;overflow:auto;padding:4px 8px;font-size:23px;line-height:1.2}
.abm-priorities{margin:0 0 8px;color:var(--ink)}
.aspirin-bleeding-management table{width:100%;border-collapse:collapse;table-layout:fixed;font-size:inherit;line-height:inherit}
.aspirin-bleeding-management th,.aspirin-bleeding-management td{padding:5px 12px;border-bottom:1px solid var(--line);text-align:left;vertical-align:middle}
.aspirin-bleeding-management thead{background:#edf3f8;color:#2e5faa;font-size:18px}
.aspirin-bleeding-management th:nth-child(1){width:33%}.aspirin-bleeding-management th:nth-child(2){width:28%}.aspirin-bleeding-management th:nth-child(3){width:39%}
.aspirin-bleeding-management tbody th{font-weight:700}.aspirin-bleeding-management tbody tr:nth-child(even){background:#f7f9fa}
.aspirin-bleeding-management .abm-setting{display:block;font-size:21px;font-weight:400;margin-top:3px}
.aspirin-bleeding-management [data-platelets=harm] td:last-child strong{color:var(--red)}
.aspirin-bleeding-management [data-platelets=consider] td:last-child strong{color:#7443a1}
.abm-ddavp{margin:8px 0 0;padding:8px 12px;background:#f1eaf7;border-left:4px solid #7c55ad}
@media(max-width:600px){.drug-expanded .vessel-figure:has(.aspirin-bleeding-management){height:auto;min-height:0;margin:12px 0;overflow:visible}.aspirin-bleeding-management{height:auto;padding:4px 0;font-size:17px}.aspirin-bleeding-management table{table-layout:auto;min-width:760px}.aspirin-bleeding-management thead{font-size:15px}.aspirin-bleeding-management .abm-setting{font-size:16px}.abm-priorities,.abm-ddavp{position:sticky;left:0;max-width:calc(100vw - 34px)}}
.other-antiplatelet-summary{padding-top:24px;font-size:30px;line-height:1.35}
.other-antiplatelet-summary ul{gap:26px}
.other-antiplatelet-summary .other-antiplatelet-warning,.other-antiplatelet-summary .other-antiplatelet-warning strong{color:var(--red)}
.other-antiplatelet-summary .other-antiplatelet-detail{display:block;margin-top:5px;font-size:.8em;color:var(--ink)}
@media(max-width:600px){.drug-expanded .vessel-figure:has(.ap-summary){height:auto;min-height:0;overflow:visible;margin:12px 0}.ap-summary{height:auto;overflow:visible;padding:6px 0;font-size:20px;line-height:1.4}.ap-summary ul{padding-left:24px;gap:14px}.ap-summary li{padding-left:2px}}
@media(prefers-reduced-motion:reduce){.aspirin-svg *{animation:none!important}}
@media(max-width:600px){.sections{gap:0 16px}.sections button{font-size:14px;white-space:normal}.drug-expanded .vessel-figure{height:300px}.drug-expanded .vessel-figure>svg{width:1110px}.drug-tools{display:block;padding:10px 0}.drug-tools>div{flex-wrap:wrap;margin-top:9px}.drug-tools button{font-size:14px;min-height:44px}.drug-stage-nav{display:block}.drug-stage-nav select{min-width:0;width:100%;font-size:16px;margin-top:8px}.drug-stage-nav span{display:block;margin-top:8px;font-size:13px}.drug-expanded.quiz-expanded .vessel-figure{height:auto;margin:10px 0;overflow:visible}.ap-quiz{overflow:visible;font-size:18px}.ap-quiz h3{font-size:21px}.ap-question-tabs{flex-wrap:wrap}.ap-question-tabs button{font-size:14px;min-height:44px}.ap-answers{grid-template-columns:1fr}.ap-answers button{font-size:17px}.ap-feedback{font-size:16px}}
:where(dialog) .p2-frequency-scroll{overflow-x:auto;max-width:100%;margin:14px 0}
:where(dialog) .p2-frequency-scroll .p2-data-table{min-width:560px;font-size:15px}
:where(dialog) .p2-frequency-scroll caption{text-align:left;font-weight:700;margin-bottom:8px}
:where(dialog) .p2-frequency-scroll thead{background:#edf3f8}
:where(dialog) .p2-frequency-scroll th,:where(dialog) .p2-frequency-scroll td{vertical-align:top}